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Tris(hydroxymethyl)aminomethane

Other Names:2-Amino-2-hydroxymethyl-1,3-propanediol;Tromethamine;Tris
Specification: Industrial Grade ≥99.5%; Pharma Grade ≥99.8%; Cosmetic Grade
Appearance: White crystalline Powder
cas no.: 77-86-1
Molecular Formula: C4H11NO3
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Packing: 25kg/bag;1000kg/bag
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Product Description

What is Tris(hydroxymethyl)aminomethane?

Tris(hydroxymethyl)aminomethane is a biological buffer used to stabilize pH in aqueous solutions, particularly in laboratory settings and product formulations. Its buffering range is typically between pH 7-9, making it ideal for a variety of biological processes, including enzyme reactions, DNA extraction, and protein purification. Tris is known for its biocompatibility, making it a preferred choice for life sciences, biotechnology, and pharmaceutical applications.

Common uses of Tris(hydroxymethyl)aminomethane include:

Biochemical & Molecular Biology: Enzyme studies, DNA/RNA extraction, and electrophoresis.
Pharmaceutical Industry: Drug formulations, stability studies, and pH regulation in intravenous solutions.
Cosmetics & Personal Care: pH adjustment in skin care formulations like lotions, creams, and serums.
Laboratory & Research: Cell culture medium preparation, protein analysis, and enzyme assay buffers.

Key Benefits of Tris(hydroxymethyl)aminomethane

Highly Effective pH Control
Tris provides excellent pH stability within a physiological range, making it an essential tool for maintaining consistency in experimental setups, pharmaceutical products, and cosmetic formulations.
Biocompatibility
Tris is widely accepted in biological and pharmaceutical applications due to its biocompatibility, ensuring that it does not interfere with biological processes and does not introduce toxicity.
Versatile Applications
Whether in scientific research, drug development, or cosmetic products, Tris is a versatile buffering agent, allowing manufacturers to create stable and reliable products across industries.
High Purity
For sensitive applications, Tris is available in high-purity grades, ensuring minimal impurities and reliable performance. This makes it suitable for pharmaceutical formulations and biotechnology applications.
Cost-Effective
As a widely used buffering agent, Tris is available at competitive prices, making it a cost-effective solution for large-scale industrial use, particularly in laboratories, R&D, and manufacturing facilities.

Main Applications

The Applications of Tris(hydroxymethyl)aminomethane

Tris is an important biological buffer with a buffer range of 7.0-9.0. Tris is widely used in the preparation of buffers in biochemistry, molecular biology, and other fields, and also can be used in the preparation of in vitro diagnostic reagents.
Tris is an important pharmaceutical intermediate, which can be used to synthesize dexketoprofen tromethamine, ketoprofen tromethamine, fosfomycin tromethamine, carboprost tromethamine, and other drugs.
Tris can be used as a pharmaceutical adjuvant in preparations such as contrast agents, biological preparations, oral grades, and eye drops.
Tris is widely used as a solvent for nucleic acids and proteins.
Tris can also be used as a pH adjuster, vulcanization accelerator, cosmetics(cream, lotion), mineral oil, paraffin emulsifier, activated carbon absorbent, and other fields.

Biological Buffer

Intermediate

Contrast Agent

Eye Drops

Solvents

Cosmetics

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Tris(hydroxymethyl)aminomethane hydrochloride

Other Names:2-Amino-2-hydroxymethyl-1,3-propanediol hydrochloride; Tris Hydrochloride; Tris HCL
Specification: 99.0%-101.0%
Appearance: White crystalline Powder
cas no.: 1185-53-1
Molecular Formula: C4H11NO3·HCL
Molecular Weight: 157.60
Free samples available
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Packing: 25kg/bag;1000kg/bag
Over 20+ years of experience
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Main Applications

The Applications of Tris(hydroxymethyl)aminomethane Hydrochloride

Tris HCL is a commonly used biological buffer with a buffer range of 7.5-8.5. Tris HCL is used to adjust the pH value of the solution or to stabilize the pH value, and it is also often used for the growth of protein crystals under different pH conditions.
Tris HCL is also an intermediate for the preparation of surfactants, vulcanization accelerators, and some drugs.
Tris HCL is also used as a titration standard.
Tris HCL is widely used as a solvent for nucleic acids and proteins.